Barcelona eased to a 3-0 win at Spartak Moscow, with Dani Alves and Messi doing the job for the Catalans.

In Turin, Juventus produced a stunning display to thrash defending champions Chelsea 3-0 and leave them on the verge of elimination.

Ten-man Valencia held Bayern Munich to a 1-1 draw to join the Bavarians to the knockouts, with Sofiane Feghouli and Thomas Muller on target.

Manchester United, already through, suffered a 1-0 defeat at Galatasaray with their reserve team.