كتب : Ahmad Saied
The former world champions took the lead in the 60th minute through left-back Marcelo before Vagner Love doubled the lead 13 minutes later.
This was Brazil's second game in London after crushing arch-rivals Argentina 3-0 at Arsenal's Emirates Stadium on Sunday.
FIFA Best Footballer of the Year Ronaldinho took part in the game after he was sidelined against Argentina through injury.
After an eventless first-half, 18-year-old Marcello marked his international debut when he unleashed a powerful left-footer home from outside the area.
Love sealed the win when he headed a Cicinho cross past Wales keeper Paul Jones in the 73rd minute.